Immunodeficient rates for cancer xenografts and humanization of the liver and immune system

Sponsored by Hera Biolabs

Novel gene edited rat models exhibit enhanced immunodeficiency and engraftment of human tumors. Rats can produce larger samples for analysis and in many ways are more physiologically similar to humans than mice. Applications discussed include: efficacy and toxicity in a single animal, more precise surgical manipulations and better in-vivo imaging